Search results for "Web Browser"
showing 10 items of 11 documents
HIPPIE v2.0: Enhancing meaningfulness and reliability of protein-protein interaction networks
2016
The increasing number of experimentally detected interactions between proteins makes it difficult for researchers to extract the interactions relevant for specific biological processes or diseases. This makes it necessary to accompany the large-scale detection of protein-protein interactions (PPIs) with strategies and tools to generate meaningful PPI subnetworks. To this end, we generated the Human Integrated Protein-Protein Interaction rEference or HIPPIE (http://cbdm.uni-mainz.de/hippie/). HIPPIE is a one-stop resource for the generation and interpretation of PPI networks relevant to a specific research question. We provide means to generate highly reliable, context-specific PPI networks …
Compendium of TCDD-mediated transcriptomic response datasets in mammalian model systems.
2017
Background 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is the most potent congener of the dioxin class of environmental contaminants. Exposure to TCDD causes a wide range of toxic outcomes, ranging from chloracne to acute lethality. The severity of toxicity is highly dependent on the aryl hydrocarbon receptor (AHR). Binding of TCDD to the AHR leads to changes in transcription of numerous genes. Studies evaluating the transcriptional changes brought on by TCDD may provide valuable insight into the role of the AHR in human health and disease. We therefore compiled a collection of transcriptomic datasets that can be used to aid the scientific community in better understanding the transcriptiona…
MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation
2015
Accepted Article
A Web Application for Interactive Visualization of European Basketball Data
2020
The statistical analysis of basketball games is a fast-growing field. Certainly, basketball data are scientifically relevant because an appropriate analysis provides a great deal of information about the performance of both players and teams. The number of games played each season generates a large amount of data worth analyzing. Basketball analytics is well established in U.S. leagues. In Europe, however, it has not been duly developed. This study focuses on the top three European team competitions: the EuroLeague, the EuroCup, and the Spanish ACB (Association of Basketball Clubs, acronym in Spanish) league. Their official websites provide access to game data for anyone who is interested, …
MGFM: a novel tool for detection of tissue and cell specific marker genes from microarray gene expression data
2015
Background Identification of marker genes associated with a specific tissue/cell type is a fundamental challenge in genetic and cell research. Marker genes are of great importance for determining cell identity, and for understanding tissue specific gene function and the molecular mechanisms underlying complex diseases. Results We have developed a new bioinformatics tool called MGFM (Marker Gene Finder in Microarray data) to predict marker genes from microarray gene expression data. Marker genes are identified through the grouping of samples of the same type with similar marker gene expression levels. We verified our approach using two microarray data sets from the NCBI’s Gene Expression Omn…
Improving Web Prefetching by Making Predictions at Prefetch
2007
Most of the research attempts to improve Web prefetching techniques have focused on the prediction algorithm with the objective of increasing its precision or, in the best case, to reduce the user's perceived latency. In contrast, to improve prefetching performance, this work concentrates in the prefetching engine and proposes the Prediction at Prefetch (P@P) technique. This paper explains how a prefetching technique can be extended to include our P@P proposal on real world conditions without changes in the web architecture or HTTP protocol. To show how this proposal can improve prefetching performance an extensive performance evaluation study has been done and the results show that P@P can…
IMFLer: A Web Application for Interactive Metabolic Flux Analysis and Visualization.
2021
Increasing genome-wide data in biological sciences and medicine has contributed to the development of a variety of visualization tools. Several automatic, semiautomatic, and manual visualization tools have already been developed. Some even have integrated flux balance analysis (FBA), but in most cases, it depends on separately installed third party software that is proprietary and does not allow customization of its functionality and has many restrictions for easy data distribution and analysis. In this study, we present an interactive metabolic flux analyzer and visualizer (IMFLer)-a static single-page web application that enables the reading and management of metabolic model layout maps, …
BANΔIT: B’‐factor Analysis for Drug Design and Structural Biology
2020
The analysis of B‐factor profiles from X‐ray protein structures can be utilized for structure‐based drug design since protein mobility changes have been associated with the quality of protein‐ligand interactions. With the BANΔIT (B’‐factor analysis and ΔB’ interpretation toolkit), we have developed a JavaScript‐based browser application that provides a graphical user interface for the normalization and analysis of B’‐factor profiles. To emphasize the usability for rational drug design applications, we have analyzed a selection of crystallographic protein‐ligand complexes and have given exemplary conclusions for further drug optimization including the development of a B’‐factor‐supported pha…
Delivering Services to Residential Appliances by Utilizing Remote Resource Awareness
2008
Service providers are nowadays offering a variety of services, and in particular multimedia content delivery. Besides, consumer appliances are increasingly becoming digitalized including support for communication networks. However, it is difficult, and in many cases impossible, to use these services with standard consumer appliances, such as TV and media player devices. Rather, usage is often restricted so that they can only be accessed through web browsers from PCs, mobile phones and similar terminals. This is unfortunate, because dedicated consumer appliances are often better suited to handle the content and thereby give consumers a better experience. Within this paper, three design appro…
Technology standard diffusion and negative network externalities: a lesson from the third Browser War
2009
This paper presents a new model for technology standard diffusion that highlights the importance of negative network externalities in some fields of technology product such as web browsers. Again, as often happened in this research field, motivation and suggestion for such a research has been acquired from the evolution of the web browser war. So, in the paper, the main literature concerning standard diffusion has been reviewed in conjunction with web browser evolution, and the necessity of a new development of technology standard diffusion models is highlighted and supported by empirical evidences.